Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987134 | 0.85 | KDM4E (0.34) | CNR2CNR1HTTL3MBTL1KDM4E | |
| SCHEMBL22987087 | 0.81 | ALDH1A1 (0.46) | HTTL3MBTL1SMN1; SMN2PTGER4KDM4E | |
| SCHEMBL22987109 | 0.79 | NPC1 (0.44) | CNR2CNR1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8048655 | 0.71 | HTT (0.33) | HTTL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22987071 | 0.70 | ESR1 (0.40) | HTTSMN1; SMN2TAS1R3TAS1R1PTGER4 | |
| SCHEMBL9593911 | 0.69 | HPGD (0.36) | CNR2CNR1HTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL27461280 | 0.69 | PKM (0.37) | CNR2CNR1HTTL3MBTL1KDM4E | |
| SCHEMBL8863114 | 0.69 | P2RX7 (0.41) | HTTSMN1; SMN2TAS1R3TAS1R1KDM4E | |
| SCHEMBL1005961 | 0.68 | HDAC6 (0.43) | HTTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5787161 | 0.68 | CA12 (0.54) | CNR2L3MBTL1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3586838-B1 | AMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| EP-3586838-B1 | AMIDE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-27 | — | — | EP | disclosed |
| US-10925848-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-02-23 | — | — | US | disclosed |
| US-10925848-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-02-23 | — | — | US | disclosed |
| CN-110325184-A | Amide derivatives | 第一三共株式会社 | 2019-10-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10925848-B2 | Amide derivative | IDO1, IDO2, TPH1 | CNR2 102/4885CNR1 88/4885HTT 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.