Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19733437 | 0.83 | ALDH1A1 (0.38) | LMNAFOLH1TSHR | |
| SCHEMBL20393509 | 0.82 | — | — | |
| SCHEMBL27102371 | 0.81 | — | — | |
| SCHEMBL3078846 | 0.78 | TSHR (0.45) | CNR1KDM4ESOAT1LMNAMEN1 | |
| SCHEMBL9883725 | 0.77 | SMN1; SMN2 (0.36) | CNR1KDM4ESOAT1LMNAMEN1 | |
| SCHEMBL19084471 | 0.76 | CASP2 (0.41) | KDM4EMEN1FAAHKMT2A | |
| SCHEMBL2863391 | 0.75 | FOLH1 (0.32) | LMNAFOLH1TSHR | |
| SCHEMBL31457164 | 0.75 | TSHR (0.48) | LMNAMEN1KMT2ATSHR | |
| SCHEMBL12656182 | 0.75 | TSHR (0.57) | LMNACYP1A2KMT2AFOLH1TSHR | |
| SCHEMBL5067235 | 0.74 | TSHR (0.48) | KDM4ESOAT1LMNAMEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778601-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |