Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20340740 | 0.87 | CASP2 (0.47) | CASP2NAAAEPHX2SLC6A5FAAH | |
| SCHEMBL12248329 | 0.87 | CASP2 (0.40) | CASP2NAAAEPHX2SLC6A5ADRA1A | |
| SCHEMBL21892050 | 0.81 | LMNA (0.58) | CASP2NAAAEPHX2SLC6A5ADRA1A | |
| SCHEMBL11987678 | 0.79 | CASP2 (0.47) | CASP2NAAAEPHX2SLC6A5ADRA1A | |
| SCHEMBL31506418 | 0.79 | CNR1 (0.42) | FAAHMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28343752 | 0.78 | CASP2 (0.61) | CASP2NAAAEPHX2SLC6A5FAAH | |
| SCHEMBL22987326 | 0.76 | CNR1 (0.33) | FAAHKDM4EMEN1KMT2A | |
| SCHEMBL1940161 | 0.76 | CASP2 (0.54) | CASP2NAAAEPHX2SLC6A5FAAH | |
| SCHEMBL10051008 | 0.76 | CASP2 (0.57) | CASP2NAAAEPHX2SLC6A5FAAH | |
| SCHEMBL24450766 | 0.75 | TSHR (0.41) | CASP2NAAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10010562-B2 | Dual molecular delivery of oligonucleotides and peptide containing conjugates | MERCK SHARP & DOHME CORP. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20170189441-A1 | DUAL MOLECULAR DELIVERY OF OLIGONUCLEOTIDES AND PEPTIDE CONTAINING CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10010562-B2 | Dual molecular delivery of oligonucleotides and peptide containing conjugates | DCLRE1A, DCLRE1B, LNPEP | CASP2 3603/4885NAAA 4147/4885EPHX2 2055/4885 |
| US-20170189441-A1 | DUAL MOLECULAR DELIVERY OF OLIGONUCLEOTIDES AND PEPTIDE CONTAINING CONJUGATES | DCLRE1A, DCLRE1B, LNPEP | CASP2 3603/4885NAAA 4147/4885EPHX2 2055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.