SCHEMBL2863391

SCHEMBL2863391

CC(C)(CCSSCCCC(N)=O)C(N)=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.32
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24761509 0.89 PAOX (0.36) FOLH1
SCHEMBL3078846 0.80 TSHR (0.45) FOLH1TSHRLMNA
SCHEMBL232206 0.78 KDM4E (0.36) LMNA
SCHEMBL154713 0.76 SOAT1 (0.39) LMNA
Hydrochloric Acid SCHEMBL561987 0.76 KDM4E (0.35) LMNA
Hydrochloric Acid SCHEMBL691540 0.76 KDM4E (0.35) LMNA
SCHEMBL181082 0.76 TSHR (0.36) TSHRLMNA
SCHEMBL5067235 0.75 TSHR (0.48) FOLH1TSHRLMNA
SCHEMBL3293803 0.75 LMNA (0.38) LMNA
SCHEMBL22987326 0.75 CNR1 (0.33) FOLH1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3545963-A1 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED Synovis Orthopedic and Woundcare, Inc. (US) 2019-10-02 EP disclosed
EP-2001521-B1 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED SYNOVIS ORTHOPEDIC AND WOUNDCARE INC (US) 2019-07-31 EP disclosed
EP-3348280-A1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS Hangzhou Dac Biotech Co., Ltd (CN) 2018-07-18 EP disclosed
US-9694037-B2 Stabilized, sterilized collagen scaffolds with active adjuncts attached SYNOVIS ORTHOPEDIC AND WOUNDCARE, INC. (US) 2017-07-04 US disclosed
US-9272004-B2 Stabilized, sterilized collagen scaffolds with active adjuncts attached SYNOVIS ORTHOPEDIC AND WOUNDCARE, INC. (US) 2016-03-01 US disclosed
US-20100266559-A1 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED SYNOVIS ORTHOPEDIC AND WOUNDCARE, INC. (US) 2010-10-21 US disclosed
US-20090196898-A1 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED SYNOVIS LIFE TECHNOLOGIES, INC. 2009-08-06 US disclosed
EP-2001521-A2 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED Pegasus Biologics, Inc. (US) 2008-12-17 EP disclosed
WO-2007109180-A2 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED PEGASUS BIOLOGICS, INC. (US) 2007-09-27 WO disclosed
US-20070218038-A1 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED PEGASUS BIOLOGICS, INC. (US) 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070218038-A1 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED COL14A1, COL1A1, COL2A1 FOLH1 697/4885TSHR 3922/4885LMNA 2034/4885
US-20100266559-A1 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED COL14A1, COL1A1, COL2A1 FOLH1 697/4885TSHR 3922/4885LMNA 2034/4885
US-20090196898-A1 STABILIZED, STERILIZED COLLAGEN SCAFFOLDS WITH ACTIVE ADJUNCTS ATTACHED COL14A1, COL1A1, COL2A1 FOLH1 697/4885TSHR 3922/4885LMNA 2034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.