Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22064142 | 0.86 | CTSS (0.45) | RECQLTSHRCAPN1BIRC2ALDH1A1 | |
| SCHEMBL17570956 | 0.83 | RECQL (0.39) | RECQLTSHRCAPN1BIRC2KMT2A | |
| SCHEMBL17616958 | 0.83 | RECQL (0.39) | RECQLTSHRCAPN1BIRC2KMT2A | |
| SCHEMBL19471807 | 0.82 | RECQL (0.69) | RECQLTSHRALDH1A1KMT2ALMNA | |
| SCHEMBL20393850 | 0.80 | RECQL (0.53) | RECQLBIRC2KMT2AGAAFAAH | |
| SCHEMBL22987342 | 0.80 | RECQL (0.53) | RECQLTSHRCAPN1ALDH1A1LMNA | |
| SCHEMBL25122213 | 0.80 | RECQL (0.53) | RECQLTSHRCAPN1ALDH1A1LMNA | |
| SCHEMBL17571001 | 0.79 | RECQL (0.65) | RECQLTSHRALDH1A1KMT2ALMNA | |
| SCHEMBL22854326 | 0.79 | REN (0.39) | RECQLCAPN1KMT2AREN | |
| SCHEMBL29918018 | 0.77 | KMT2A (0.55) | CAPN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778601-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |