Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440949 | 0.88 | TERT (0.35) | TERT | |
| SCHEMBL30360564 | 0.84 | SMN1; SMN2 (0.38) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL22987402 | 0.84 | LMNA (0.37) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL14554066 | 0.80 | HPGD (0.37) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL15426045 | 0.80 | MEN1 (0.40) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL43231 | 0.80 | HPGD (0.36) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL13069293 | 0.80 | HPGD (0.36) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL12519066 | 0.80 | HPGD (0.36) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL8191582 | 0.80 | HPGD (0.36) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL16392777 | 0.79 | HPGD (0.32) | HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778601-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |