SCHEMBL22989218

SCHEMBL22989218

c1ccc2cc(-c3nc4ccccc4nc3-c3ccc4cc(-n5c6ccc7cccc8oc9cccc%10ccc5c(c%109)c6c78)ccc4c3)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.36
MAPK10 P53779 5/20 0.36
MAPK9 P45984 3/20 0.36
PDE10A Q9Y233 3/20 0.35
UTRN P46939 1/20 0.35
POLB P06746 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HPGD P15428 1/20 0.32
MAPK8 P45983 1/20 0.32
OPRD1 P41143 1/20 0.32
DHODH Q02127 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22989021 0.95 L3MBTL1 (0.42) L3MBTL1PDE10AADORA2AADORA1KDM4E
SCHEMBL22989223 0.94 L3MBTL1 (0.41) L3MBTL1PDE10AADORA2AADORA1KDM4E
SCHEMBL22989220 0.91 MAPT (0.34) L3MBTL1PDE10AUTRNPOLBKDM4E
SCHEMBL22989225 0.90 ALDH1A1 (0.35) L3MBTL1PDE10AKDM4EALDH1A1LMNA
SCHEMBL22989224 0.87 HPGD (0.31) PDE10AHPGD
SCHEMBL22989016 0.87 ATM (0.38) MAPK10MAPK9UTRNADORA2AALDH1A1
SCHEMBL22989111 0.87 PDE10A (0.36) L3MBTL1MAPK10MAPK9PDE10AUTRN
SCHEMBL22989244 0.86 AKT1 (0.38) L3MBTL1PDE10AUTRNADORA2AADORA1
SCHEMBL22989065 0.85 MAPK10 (0.38) L3MBTL1MAPK10MAPK9PDE10APOLB
SCHEMBL22988910 0.84 ALDH1A1 (0.41) MAPK10MAPK9UTRNKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed