SCHEMBL22989263

SCHEMBL22989263

c1ccc2cc(-c3nc4ccccc4nc3-n3c4ccc5cccc6sc7cccc8ccc3c(c87)c4c56)ccc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 4/20 0.35
MAPK9 P45984 2/20 0.34
MAPK10 P53779 2/20 0.34
MAPK8 P45983 1/20 0.34
NQO2 P16083 1/20 0.32
DHODH Q02127 1/20 0.32
MAPT P10636 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SRC P12931 2/20 0.32
CYP17A1 P05093 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
NPSR1 Q6W5P4 2/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23031023 0.92 PDE10A (0.33) PDE10AMAPK1ALDH1A1
SCHEMBL22988950 0.89 PDE10A (0.36) PDE10AMAPTRAB9ASMN1; SMN2TDP1
SCHEMBL22988949 0.89 CASP1 (0.39) PDE10AMAPK10DHODHTDP1NPSR1
SCHEMBL22988940 0.89 CASP1 (0.40) PDE10AMAPTTDP1NPSR1MEN1
SCHEMBL22988944 0.89 PDE10A (0.31) PDE10A
SCHEMBL22989065 0.87 MAPK10 (0.38) PDE10AMAPK9MAPK10MAPK8MAPT
SCHEMBL22989111 0.84 PDE10A (0.36) PDE10AMAPK9MAPK10MAPK8NQO2
SCHEMBL22988947 0.84 ALDH1A1 (0.33) SMN1; SMN2MEN1KMT2AL3MBTL1POLB
SCHEMBL22988951 0.84 KDM4E (0.35) KDM4EL3MBTL1
SCHEMBL23030496 0.84 PDE10A (0.33) PDE10AMAPTNPSR1MEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed