Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26528126 | 0.77 | KDM4E (0.35) | — | |
| SCHEMBL30888611 | 0.77 | MAPT (0.35) | PNMT | |
| SCHEMBL22989890 | 0.77 | SOS1 (0.31) | SOS1 | |
| SCHEMBL30888535 | 0.76 | SOS1 (0.30) | SOS1 | |
| SCHEMBL19475118 | 0.74 | NLRP3 (0.38) | — | |
| SCHEMBL30365888 | 0.73 | ACHE (0.35) | PNMT | |
| SCHEMBL29284972 | 0.73 | ACHE (0.35) | PNMT | |
| SCHEMBL22989448 | 0.73 | SOS1 (0.32) | SOS1 | |
| SCHEMBL30888576 | 0.73 | MEN1 (0.31) | — | |
| SCHEMBL30888674 | 0.73 | DRD2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027943-A1 | PYRIMIDINOPYRIDAZINONE DERIVATIVE AND MEDICAL USE THEREOF | 正大天晴药业集团南京顺欣制药有限公司 | 2021-02-18 | — | — | WO | disclosed |