Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22989439 | 0.82 | GPR55 (0.53) | PKMALDH1A1GPR55GAAMEN1 | |
| SCHEMBL22989954 | 0.79 | KIT (0.54) | PKMALDH1A1GPR55GAAMEN1 | |
| SCHEMBL22989951 | 0.79 | MAPT (0.48) | PKMALDH1A1GPR55GAAMAPK1 | |
| SCHEMBL6667999 | 0.74 | PKM (0.63) | PKMALDH1A1GPR55GAAMEN1 | |
| SCHEMBL5864286 | 0.74 | HTR2C (0.51) | ALDH1A1GPR55MEN1KMT2AMAPT | |
| SCHEMBL22989952 | 0.73 | MAPT (0.71) | PKMALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8352589 | 0.72 | HTR3A (0.61) | — | |
| Hydrochloric Acid SCHEMBL6761545 | 0.71 | PKM (0.61) | PKMALDH1A1GPR55GAAMEN1 | |
| SCHEMBL14380419 | 0.69 | PKM (0.56) | PKMALDH1A1GPR55GAAMEN1 | |
| SCHEMBL2628832 | 0.69 | GPR55 (0.75) | PKMALDH1A1GPR55GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027943-A1 | PYRIMIDINOPYRIDAZINONE DERIVATIVE AND MEDICAL USE THEREOF | 正大天晴药业集团南京顺欣制药有限公司 | 2021-02-18 | — | — | WO | disclosed |