Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393001 | 0.94 | KDM4E (0.54) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL22990582 | 0.87 | KDM4E (0.57) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL20225058 | 0.87 | KDM4E (0.57) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL20434918 | 0.87 | KDM4E (0.57) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL22524143 | 0.87 | TAS1R3 (0.47) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL21376540 | 0.86 | ALDH1A1 (0.55) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL18963575 | 0.86 | ALDH1A1 (0.55) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL22087964 | 0.85 | KDM4E (0.55) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL24513564 | 0.82 | KDM4E (0.52) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL18963691 | 0.82 | KDM4E (0.58) | TAS1R3TAS1R1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180683-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-09-26 | — | — | WO | disclosed |