SCHEMBL22990767

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28763851	1.00	ALDH1A1 (0.46)	ALDH1A1TSHRKDM4ESLC1A3SLC1A2
	SCHEMBL29177665	0.83	ALDH1A1 (0.42)	ALDH1A1TSHRKDM4ESLC1A3SLC1A2
	SCHEMBL28763892	0.81	ALDH1A1 (0.42)	ALDH1A1TSHRKDM4EKMT2ANPC1
	SCHEMBL28763890	0.81	ALDH1A1 (0.42)	ALDH1A1TSHRKDM4EKMT2ANPC1
	SCHEMBL22981289	0.80	ALDH1A1 (0.43)	ALDH1A1TSHRKDM4EKMT2ANPC1
	SCHEMBL22289684	0.79	MLYCD (0.39)	KDM4EKMT2APOLQ
	SCHEMBL22289683	0.79	MLYCD (0.39)	KDM4EKMT2APOLQ
	SCHEMBL29177690	0.78	EGFR (0.39)	ALDH1A1SLC1A3SLC1A2SLC1A1LMNA
	SCHEMBL23537716	0.77	ALDH1A1 (0.50)	ALDH1A1TSHRKMT2ANPC1RAB9A
	SCHEMBL30638957	0.76	ALDH1A1 (0.51)	ALDH1A1TSHRKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.