SCHEMBL2299304

SCHEMBL2299304

CC(OC(=O)OC(C)C(F)(F)C(F)C(F)(F)F)C(F)(F)C(F)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2299305 0.85 ALDH1A1 (0.33) ALDH1A1TSHRHSD17B10
SCHEMBL2038198 0.82
SCHEMBL9679748 0.79 TSHR (0.36) TSHR
SCHEMBL9681129 0.79 TSHR (0.36) ALDH1A1TSHR
SCHEMBL12095052 0.79 RORC (0.34) RORCTSHR
SCHEMBL701888 0.79 RORC (0.34) RORCTSHR
SCHEMBL649650 0.74 MEN1 (0.31)
SCHEMBL16754716 0.72 TSHR (0.32) TSHR
SCHEMBL16985214 0.71 ABHD6 (0.33) RORC
SCHEMBL700475 0.70 TSHR (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406977-B2 Fluorinated compounds for use in lithium battery electrolytes 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-08-02 US disclosed
EP-2247686-B1 HEAT TRANSFER APPARATUS AND METHODS INCLUDING HYDROFLUOROCARBONATES 3M INNOVATIVE PROPERTIES CO (US) 2014-12-24 EP disclosed
EP-2637245-A1 Fluorinated compounds for use in lithium battery electrolytes 3M Innovative Properties Company (US) 2013-09-11 EP disclosed
US-20130224605-A1 FLUORINATED COMPOUNDS FOR USE IN LITHIUM BATTERY ELECTROLYTES 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-08-29 US disclosed
US-8435679-B2 Fluorinated compounds for use in lithium battery electrolytes 3M INNOVATIVE PROPERTIES COUNSEL (US) 2013-05-07 US disclosed
US-8003004-B2 Heat transfer apparatus and methods including hydrofluorocarbonates 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-08-23 US disclosed
EP-2247686-A1 HEAT TRANSFER APPARATUS AND METHODS INCLUDING HYDROFLUOROCARBONATES 3M Innovative Properties Company (US) 2010-11-10 EP disclosed
US-20100104950-A1 FLUORINATED COMPOUNDS FOR USE IN LITHIUM BATTERY ELECTROLYTES GELION TECHNOLOGIES PTY LTD (AU) 2010-04-29 US disclosed
EP-2108209-A1 FLUORINATED COMPOUNDS FOR USE IN LITHIUM BATTERY ELECTROLYTES 3M Innovative Properties Company (US) 2009-10-14 EP disclosed
WO-2009094278-A1 HEAT TRANSFER APPARATUS AND METHODS INCLUDING HYDROFLUOROCARBONATES 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-07-30 WO disclosed
US-20090183856-A1 HEAT TRANSFER APPARATUS AND METHODS INCLUDING HYDROFLUOROCARBONATES 3M INNOVATIVE PROPERTIES COMPANY 2009-07-23 US disclosed
WO-2008079670-A1 FLUORINATED COMPOUNDS FOR USE IN LITHIUM BATTERY ELECTROLYTES 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104950-A1 FLUORINATED COMPOUNDS FOR USE IN LITHIUM BATTERY ELECTROLYTES FLNB, FLNA, HCN2 RORC 996/4885ALDH1A1 1056/4885TSHR 3034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.