SCHEMBL22993535

SCHEMBL22993535

Fc1cc(-c2cc(-c3cc4ccccc4c4ccccc34)c3cc4cc(-c5ccc(OC(F)(F)F)cc5)cc(-c5cc6ccccc6c6ccccc56)c4cc3c2)cc(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 5/20 0.37
CYP11B2 P19099 5/20 0.37
ACP1 P24666 1/20 0.37
KIF11 P52732 1/20 0.36
AURKA O14965 1/20 0.36
TPX2 Q9ULW0 1/20 0.36
ALOX5AP P20292 1/20 0.34
FEN1 P39748 1/20 0.34
CHRM5 P08912 1/20 0.34
SCN5A Q14524 1/20 0.33
MMP3 P08254 1/20 0.33
EPHX2 P34913 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26803588 0.90 KIF11 (0.34) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993125 0.90 KIF11 (0.34) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993141 0.84 KIF11 (0.39) CYP11B1CYP11B2KIF11EPHX2
SCHEMBL22993350 0.84 KIF11 (0.38) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993345 0.82 KIF11 (0.34) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993508 0.82 KIF11 (0.34) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993143 0.81 CYP11B1 (0.36) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993150 0.81 KIF11 (0.37) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22993525 0.80 GPR84 (0.35) CYP11B1CYP11B2ACP1KIF11AURKA
SCHEMBL22992953 0.80 GPR84 (0.35) CYP11B1CYP11B2ACP1KIF11AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed