SCHEMBL22996017

SCHEMBL22996017

CO[C@@H]1C[C@@H](COC(C)C)N(C(C)=O)C1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MMP2 P08253 1/20 0.33
▸ ANPEP P15144 1/20 0.33
▸ HCRTR2 O43614 1/20 0.30
▸ DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25492845 1.00 MMP2 (0.33) MMP2ANPEPHCRTR2DPP4
SCHEMBL24375001 0.88 ATM (0.33) HCRTR2DPP4
SCHEMBL18513346 0.88 ATM (0.33) HCRTR2DPP4
SCHEMBL12211119 0.85 ADORA2A (0.37) MMP2ANPEP
SCHEMBL20209391 0.85 ADORA2A (0.37) MMP2ANPEP
SCHEMBL23710651 0.85 HCRTR2 (0.35) HCRTR2
SCHEMBL24119964 0.85 CHRNB2 (0.32) DPP4
SCHEMBL18513313 0.85 HCRTR2 (0.35) HCRTR2
SCHEMBL22372628 0.84 — —
SCHEMBL24098413 0.84 HCRTR2 (0.31) MMP2ANPEPHCRTR2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230193284-A1 TRANSMEMBRANE SERINE PROTEASE 2 (TMPRSS2) IRNA COMPOSITIONS AND METHODS OF USE THEREOF BANK OF AMERICA, N.A. 2023-06-22 — — US disclosed
US-20220389419-A1 MODIFIED OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2022-12-08 — — US disclosed
WO-2021030522-A1 SMALL RIBOSOMAL PROTEIN SUBUNIT 25 (RPS25) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF ALNYLAM PHARMACEUTICALS, INC. (US) 2021-02-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389419-A1 MODIFIED OLIGONUCLEOTIDES EIF2AK2, RNASE1, SNRPE MMP2 3953/4885ANPEP 3338/4885HCRTR2 4164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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