SCHEMBL229965

SCHEMBL229965

CCOC(CC)C(O[SiH3])(OCC)OCC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28411954 0.83
SCHEMBL8536888 0.83
SCHEMBL28714186 0.79 LMNA (0.32)
SCHEMBL28914346 0.77 SMPD1 (0.33)
SCHEMBL229913 0.77 THRB (0.33) THRB
SCHEMBL9759751 0.75 TSHR (0.31)
SCHEMBL229966 0.75
SCHEMBL28659320 0.75
SCHEMBL5837304 0.74 THRB (0.31) THRB
SCHEMBL19356669 0.73 THRB (0.33) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3088961-B1 CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMATION DEVICE CANON KK (JP) 2021-03-10 EP disclosed
US-10459356-B2 Charging member, process cartridge and electrophotographic image forming apparatus CANON KABUSHIKI KAISHA (JP) 2019-10-29 US disclosed
US-10078286-B2 Charging member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-09-18 US disclosed
US-10036971-B2 Charging member, process cartridge, and electrophotographic image forming apparatus CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-9989879-B2 Charging member, process cartridge and electrophotographic image forming apparatus CANON KABUSHIKI KAISHA (JP) 2018-06-05 US disclosed
EP-3121655-B1 CHARGING MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS CANON KK (JP) 2018-05-23 EP disclosed
US-20180101106-A1 CHARGING MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-12 US disclosed
EP-3121655-A1 CHARGING MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS Canon Kabushiki Kaisha (JP) 2017-01-25 EP disclosed
US-20160378010-A1 CHARGING MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-12-29 US disclosed
EP-3088961-A1 CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMATION DEVICE Canon Kabushiki Kaisha (JP) 2016-11-02 EP disclosed
US-20160299451-A1 CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-10-13 US disclosed
US-20150331348-A1 CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-11-19 US disclosed
US-8623958-B2 Oil-in-water silicone emulsion composition DOW CORNING TORAY CO. LTD. (JP) 2014-01-07 US disclosed
EP-2406323-B1 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO LTD (JP) 2013-07-24 EP disclosed
EP-2406322-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
EP-2406323-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-01-18 EP disclosed
US-20120004354-A1 Oil-In-Water Silicone Emulsion Composition DOW TORAY CO., LTD. (JP) 2012-01-05 US disclosed
US-20110319557-A1 Oil-In-Water Silicone Emulsion Composition DOW CORNING TORAY CO., LTD. (JP) 2011-12-29 US disclosed
WO-2010104186-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed
WO-2010104185-A2 OIL-IN-WATER SILICONE EMULSION COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2010-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10036971-B2 Charging member, process cartridge, and electrophotographic image forming apparatus GNG2, NRAS, ARFGEF1 THRB 4539/4885
US-20150331348-A1 CHARGING MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS GNG2, NRAS, ARFGEF1 THRB 4539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.