Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CREB1 | P16220 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22997879 | 0.86 | LMNA (0.56) | LMNAGAANPC1RAB9APOLB | |
| SCHEMBL9778336 | 0.85 | KDM4E (0.51) | LMNAGAANPC1CYP1A2CYP2C19 | |
| SCHEMBL7622844 | 0.84 | KDM4E (0.48) | LMNAGAANPC1CYP1A2CYP2C19 | |
| SCHEMBL31281619 | 0.83 | THRA (0.44) | LMNAGAANPC1CYP1A2CYP2C19 | |
| SCHEMBL15910022 | 0.82 | LMNA (0.61) | LMNAGAANPC1RAB9APOLB | |
| SCHEMBL11092303 | 0.82 | CREB1 (0.47) | LMNAGAANPC1CYP1A2CYP2C19 | |
| SCHEMBL22872659 | 0.82 | TEAD4 (0.43) | LMNAGAANPC1CYP1A2CYP2C19 | |
| SCHEMBL23512777 | 0.82 | LMNA (0.57) | LMNAGAANPC1POLBHPGD | |
| SCHEMBL20218243 | 0.81 | TEAD4 (0.42) | LMNAGAANPC1CYP1A2CYP2C19 | |
| SCHEMBL16236042 | 0.81 | LMNA (0.52) | LMNAGAANPC1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4074709-A1 | MONOCYCLIC BETA-LACTAM COMPOUND AND USE THEREOF | Evopoint Biosciences Co., Ltd. (CN) | 2022-10-19 | — | — | EP | disclosed |
| WO-2021115444-A1 | MONOCYCLIC β-LACTAM COMPOUND AND USE THEREOF | 苏州信诺维医药科技股份有限公司 | 2021-06-17 | — | — | WO | disclosed |
| EP-3330272-B1 | FUSED TRICYCLIC HETEROCYCLIC COMPOUNDS AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME (US) | 2021-02-17 | — | — | EP | disclosed |