Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 14/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23001763 | 0.88 | HAO1 (0.52) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL23001988 | 0.85 | HAO1 (0.49) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL23001812 | 0.84 | HAO1 (0.54) | HAO1 | |
| SCHEMBL29692348 | 0.81 | HAO1 (0.58) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL23001809 | 0.81 | HAO1 (0.58) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL21296921 | 0.81 | MAPT (0.52) | GABRA2HAO1GABRB2 | |
| SCHEMBL21296961 | 0.81 | MAPT (0.45) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL23001665 | 0.81 | KDM4E (0.40) | GABRA1GABRA5GABRG2GABRB3GABRA3 | |
| SCHEMBL22795534 | 0.80 | HPGDS (0.48) | — | |
| SCHEMBL21296922 | 0.78 | NPBWR1 (0.38) | GABRA1GABRA5GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250186441-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2025-06-12 | — | — | US | disclosed |
| US-12213976-B2 | Compounds and methods for treating oxalate-related diseases | OXALURX, INC. (US) | 2025-02-04 | — | — | US | disclosed |
| CN-114980886-B | Compounds and methods for treating oxalate-related diseases | 奥沙鲁克斯公司 | 2024-08-09 | — | — | CN | disclosed |
| US-20230110495-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2023-04-13 | — | — | US | disclosed |
| US-11504367-B2 | Compounds and methods for treating oxalate-related diseases | OXALURX, INC. (US) | 2022-11-22 | — | — | US | disclosed |
| CN-114980886-A | Compounds and methods for treating oxalate-related diseases | 奥沙鲁克斯公司 | 2022-08-30 | — | — | CN | disclosed |
| EP-4017490-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | Oxalurx, Inc. (US) | 2022-06-29 | — | — | EP | disclosed |
| US-20210052586-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2021-02-25 | — | — | US | disclosed |
| WO-2021035196-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. (US) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052586-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, OAT | GABRA1 3603/4885GABRA5 3681/4885GABRG2 2917/4885 |
| US-11504367-B2 | Compounds and methods for treating oxalate-related diseases | XDH, PNPO, OAT | GABRA1 3603/4885GABRA5 3681/4885GABRG2 2917/4885 |
| US-20250186441-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, OAT | GABRA1 3603/4885GABRA5 3681/4885GABRG2 2917/4885 |
| US-20230110495-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, OAT | GABRA1 3603/4885GABRA5 3681/4885GABRG2 2917/4885 |
| US-12213976-B2 | Compounds and methods for treating oxalate-related diseases | XDH, PNPO, OAT | GABRA1 3603/4885GABRA5 3681/4885GABRG2 2917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.