⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960143 | 0.83 | ALDH1A1 (0.77) | — | |
| SCHEMBL711360 | 0.82 | RAB9A (0.75) | — | |
| SCHEMBL2216212 | 0.82 | ALDH1A1 (1.00) | — | |
| SCHEMBL2209532 | 0.80 | ALDH1A1 (0.71) | — | |
| SCHEMBL23855456 | 0.80 | — | — | |
| SCHEMBL5762863 | 0.80 | GSK3B (0.66) | — | |
| SCHEMBL4852587 | 0.79 | HPGD (0.70) | — | |
| SCHEMBL658097 | 0.78 | — | — | |
| SCHEMBL22721189 | 0.78 | ALDH1A1 (0.83) | — | |
| SCHEMBL11407883 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111205266-B | Synthetic method of 2-thiopheneacetic acid | 辽宁九华化工有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-111205266-A | Synthetic method of 2-thiopheneacetic acid | 辽宁九华化工有限公司 | 2020-05-29 | — | — | CN | claimed |
| CN-105085469-A | Preparation method of 5-chlorothienyl-2-carboxylic acid | CANGZHOU SENARY CHEMICAL SCIENCE TEC CO LTD | 2015-11-25 | — | — | CN | claimed |
| EP-2034011-B1 | CELL CLUSTER COMPRISING PLURAL KINDS OF CELLS DERIVED FROM SOMA WITH ABILITY TO FORM PRIMITIVE ORGAN-LIKE STRUCTURE | SHISEIDO CO LTD (JP) | 2013-05-22 | — | — | EP | claimed |
| US-20090306045-A1 | Inhibition of Glycogen Synthase Kinase and Methods of Treating Autoimmune or Immune Inflammatory Disease | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-10 | — | — | US | claimed |
| WO-2007075911-A2 | INHIBITION OF GLYCOGEN SYNTHASE KINASE AND METHODS OF TREATING AUTOIMMUNE OR IMMUNE INFLAMMATORY DISEASE | YALE UNIVERSITY (US) | 2007-07-05 | — | — | WO | claimed |
| EP-1243581-B1 | Pyridinium compounds useful for the treatment of AGE-related diseases | TORRENT PHARMACEUTICALS LTD (IN) | 2005-07-13 | — | — | EP | claimed |
| JP-1019006-A | — | — | None | — | — | JP | disclosed |
| CN-118184625-A | Synthesis method of 2-thiopheneacetic acid | 浙江东盈药业有限公司 | 2024-06-14 | — | — | CN | disclosed |
| US-11746331-B2 | Endodermal cell population, and method for producing cell population of any of three germ layers from pluripotent cell | KANEKA CORPORATION | 2023-09-05 | — | — | US | disclosed |
| EP-4194549-A1 | ENDODERMAL CELL POPULATION, AND METHOD FOR PRODUCING CELL POPULATION OF ANY OF THREE GERM LAYERS FROM PLURIPOTENT CELL | Kaneka Corporation (JP) | 2023-06-14 | — | — | EP | disclosed |
| US-20230174945-A1 | METHOD FOR INDUCING DIFFERENTIATION INTO PANCREATIC ALPHA CELLS | KANEKA CORPORATION (JP) | 2023-06-08 | — | — | US | disclosed |
| CN-114605375-B | Synthetic method of 2-thiopheneacetic acid | 沈阳化工研究院有限公司 | 2023-04-11 | — | — | CN | disclosed |
| US-4258040-A | Cephalosporin compounds | MERCK & CO., INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4105663-A | HYPOTENSIVE, BLOCKING AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |
| US-4093628-A | HYPOTENSIVE AGENTS, BLOCKING AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4082772-A | HYPOTENSIVE AGENTS, B-ADRENERGIC BLOCKING AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |
| US-4060687-A | Cephalosporins having a 3-α substituted alkyl grouping | MERCK & CO., INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-4024156-A | Thiophene ethanolamines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3947413-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-03-30 | — | — | US | disclosed |