Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 3/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16897737 | 1.00 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2RAB9AMAPTSCN1A | |
| SCHEMBL12321236 | 0.89 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2RAB9AMAPTSCN1A | |
| SCHEMBL30142083 | 0.89 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2RAB9AMAPTSCN1A | |
| SCHEMBL5844533 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2RAB9AMAPTSCN1A | |
| Hydrochloric Acid SCHEMBL5843353 | 0.83 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2RAB9AMAPTSCN1A | |
| SCHEMBL21765657 | 0.83 | NAAA (0.48) | ALDH1A1SMN1; SMN2CHRM3CHRM1CHRM4 | |
| SCHEMBL2253713 | 0.83 | — | — | |
| SCHEMBL2005308 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2RAB9AMAPTSCN1A | |
| SCHEMBL25475322 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2RAB9AMAPTSCN1A | |
| SCHEMBL17296564 | 0.82 | NAAA (0.60) | ALDH1A1SMN1; SMN2RAB9AMAPTSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11826435-B2 | Conduritol aziridine derivatives and uses thereof | UNIVERSITY OF SASKATCHEWAN (CA) | 2023-11-28 | — | — | US | disclosed |
| US-20210052752-A1 | CONDURITOL AZIRIDINE DERIVATIVES AND USES THEREOF | UNIVERSITY OF SASKATCHEWAN (CA) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11826435-B2 | Conduritol aziridine derivatives and uses thereof | GAA, MAN2B1, GBA3 | ALDH1A1 197/4885SMN1; SMN2 3521/4885RAB9A 196/4885 |
| US-20210052752-A1 | CONDURITOL AZIRIDINE DERIVATIVES AND USES THEREOF | GAA, MAN2B1, GBA3 | ALDH1A1 197/4885SMN1; SMN2 3521/4885RAB9A 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.