Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.32 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.32 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GALK1 | P51570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23005174 | 0.87 | FPR2 (0.38) | FPR2HIF1AFOLH1MTHFD1MTHFD2 | |
| SCHEMBL23005169 | 0.86 | FPR2 (0.39) | FPR2GSTO1HIF1AFOLH1LMNA | |
| SCHEMBL23005244 | 0.85 | FPR2 (0.38) | FPR2HIF1AFOLH1LMNAMTHFD1 | |
| SCHEMBL21494666 | 0.81 | FPR2 (0.66) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL23005112 | 0.81 | EPOR (0.33) | FPR2TRPM8 | |
| SCHEMBL23005260 | 0.77 | ALDH1A1 (0.50) | LMNAMAPTMEN1KMT2ATRPM8 | |
| SCHEMBL23005142 | 0.73 | FPR2 (0.65) | FPR2FOLH1MTHFD1MTHFD2KDM4E | |
| SCHEMBL23005143 | 0.73 | FPR2 (0.65) | FPR2FOLH1MTHFD1MTHFD2KDM4E | |
| SCHEMBL23005242 | 0.72 | RORC (0.38) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL23005116 | 0.69 | FPR2 (0.31) | FPR2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781554-B1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FOER MEDICINSK FORSKNING (SE) | 2023-06-28 | — | — | EP | disclosed |
| US-20210052587-A1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | MEDICINSK FORSKNING (SE) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052587-A1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | IL2, THPO, IL6 | FPR2 435/4885GSTO1 2048/4885HIF1A 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.