Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5258921 | 0.82 | MEN1 (0.49) | MEN1KMT2AMAPK1MAPTHSD17B10 | |
| SCHEMBL10192014 | 0.81 | HSD17B10 (0.53) | MEN1KMT2AMAPK1MAPTLMNA | |
| SCHEMBL160077 | 0.80 | NPC1 (0.54) | MEN1KMT2AMAPK1LMNAHSD17B10 | |
| SCHEMBL882949 | 0.79 | MEN1 (0.54) | MEN1KMT2ALMNAHPGDNPC1 | |
| SCHEMBL2281889 | 0.79 | HPGD (0.50) | MEN1KMT2AMAPK1MAPTLMNA | |
| SCHEMBL11874201 | 0.79 | RAB9A (0.57) | MEN1KMT2AMAPK1MAPTLMNA | |
| SCHEMBL29951102 | 0.79 | MGLL (0.68) | MAPTMGLLALDH1A1NPC1RAB9A | |
| SCHEMBL23201123 | 0.79 | HPGD (0.50) | MEN1KMT2AMAPK1MAPTLMNA | |
| SCHEMBL7012473 | 0.79 | MGLL (0.47) | MEN1KMT2AMAPK1MAPTLMNA | |
| SCHEMBL6209756 | 0.79 | MGLL (0.68) | MAPTMGLLALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3412279-B1 | NANOSTRUCTURED GELS CAPABLE OF CONTROLLED RELEASE OF ENCAPSULATED AGENTS | BRIGHAM & WOMENS HOSPITAL INC (US) | 2021-02-17 | — | — | EP | disclosed |