SCHEMBL23009356

SCHEMBL23009356

CCOC(=O)c1ccc([C@H]2CCCCN(c3ccc(C(=O)OCC)o3)CCN(c3ccc(C(=O)OCC)o3)CCN(c3ccc(C(=O)OCC)o3)CCC2)o1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
ALDH1A1 P00352 3/20 0.38
CYP2C19 P33261 2/20 0.38
TP53 P04637 1/20 0.38
GAA P10253 1/20 0.38
CYP2D6 P10635 1/20 0.38
S1PR1 P21453 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
PABPC1 P11940 1/20 0.38
EIF4H Q15056 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ITGB2 P05107 1/20 0.38
ITGAM P11215 1/20 0.38
LMNA P02545 1/20 0.38
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20190382 0.84 HDAC4 (0.49) HDAC4HDAC6ALDH1A1CYP2C19GAA
SCHEMBL20188051 0.83 HDAC4 (0.53) HDAC4HDAC6ALDH1A1GAAL3MBTL1
SCHEMBL31704814 0.76 HDAC4 (0.48) HDAC4HDAC6ALDH1A1CYP2C19TP53
SCHEMBL23621100 0.75 L3MBTL1 (0.44) HDAC4HDAC6ALDH1A1CYP2C19TP53
SCHEMBL3664445 0.73 HDAC4 (0.43) HDAC4HDAC6ALDH1A1CYP2C19TP53
SCHEMBL21510768 0.71 S1PR1 (0.53) ALDH1A1CYP2C19GAAS1PR1TDP1
SCHEMBL449698 0.67 HDAC4 (0.73) HDAC4HDAC6ALDH1A1TP53GAA
SCHEMBL28872310 0.66 S1PR1 (0.57) ALDH1A1S1PR1MEN1MAPTKMT2A
SCHEMBL1801024 0.66 ALDH1A1 (0.65) HDAC4HDAC6ALDH1A1GAAL3MBTL1
SCHEMBL25062510 0.65 ALDH1A1 (0.50) ALDH1A1CYP2C19TP53GAACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778045-A1 COMPOUND FOR RESTORING CONTAMINATED SOIL OR CONTAMINATED WATER FNG Research Co., Ltd. (KR) 2021-02-17 EP disclosed