SCHEMBL20190382

SCHEMBL20190382

CCOC(=O)c1ccc(N2CCCN(c3ccc(C(=O)OCC)o3)CCN(c3ccc(C(=O)OCC)o3)CCCN(c3ccc(C(=O)OCC)o3)CC2)o1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
ALDH1A1 P00352 6/20 0.45
TSHR P16473 1/20 0.45
ITGB2 P05107 1/20 0.42
ITGAM P11215 1/20 0.42
MAPT P10636 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
KDM4E B2RXH2 1/20 0.42
TLR2 O60603 1/20 0.42
NSD2 O96028 1/20 0.42
POLB P06746 1/20 0.42
PKM P14618 1/20 0.42
MPI P34949 1/20 0.42
GRK6 P43250 1/20 0.42
RECQL P46063 1/20 0.42
TLR1 Q15399 1/20 0.42
TLR6 Q9Y2C9 1/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20188051 0.95 HDAC4 (0.53) HDAC4HDAC6ALDH1A1TSHRMAPT
SCHEMBL23621100 0.89 L3MBTL1 (0.44) HDAC4HDAC6ALDH1A1TSHRMAPT
SCHEMBL23009356 0.84 HDAC4 (0.39) HDAC4HDAC6ALDH1A1TSHRITGB2
SCHEMBL449698 0.77 HDAC4 (0.73) HDAC4HDAC6ALDH1A1TSHRMAPT
SCHEMBL20190423 0.76 POLB (0.44) ALDH1A1MAPTL3MBTL1KDM4EPOLB
SCHEMBL29617026 0.73 HDAC4 (0.64) HDAC4HDAC6ALDH1A1TSHRMAPT
SCHEMBL20206253 0.73 POLB (0.39) ALDH1A1MAPTL3MBTL1KDM4EPOLB
SCHEMBL2075850 0.73 HDAC4 (0.58) HDAC4HDAC6ALDH1A1TSHRMAPT
SCHEMBL1801024 0.72 ALDH1A1 (0.65) HDAC4HDAC6ALDH1A1TSHRMAPT
SCHEMBL669793 0.72 HDAC4 (0.62) HDAC4HDAC6ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11274268-B2 Detergent compositions for removing heavy metals and formaldehyde FNG RESEARCH CO., LTD. (KR) 2022-03-15 US disclosed
US-11090247-B2 Compositions for protecting the skin from heavy metals and formaldehyde FNG RESEARCH CO., LTD. (KR) 2021-08-17 US disclosed
US-11090247-B2 Compositions for protecting the skin from heavy metals and formaldehyde FNG RESEARCH CO., LTD. (KR) 2021-08-17 US disclosed
US-20210207064-A1 COMPOUND FOR RESTORING CONTAMINATED SOIL OR CONTAMINATED WATER FNG RESEARCH CO., LTD. (KR) 2021-07-08 US disclosed
EP-3778045-A1 COMPOUND FOR RESTORING CONTAMINATED SOIL OR CONTAMINATED WATER FNG Research Co., Ltd. (KR) 2021-02-17 EP disclosed
WO-2020138551-A1 FILTER HAVING HEAVY METAL AND FORMALDEHYDE REMOVAL CAPABILITY (주)에프엔지리서치 2020-07-02 WO disclosed
EP-3544953-A1 COMPOSITIONS FOR PROTECTING THE SKIN FROM HEAVY METALS AND FORMALDEHYDE FNG Research Co., Ltd. (KR) 2019-10-02 EP disclosed
EP-3538631-A1 DETERGENT COMPOSITIONS FOR REMOVING HEAVY METALS AND FORMALDEHYDE FNG Research Co., Ltd. (KR) 2019-09-18 EP disclosed
WO-2018174337-A1 DETERGENT COMPOSITIONS FOR REMOVING HEAVY METALS AND FORMALDEHYDE FNG RESEARCH CO., LTD. (KR) 2018-09-27 WO disclosed
WO-2018097431-A1 COMPOSITIONS FOR PROTECTING THE SKIN FROM HEAVY METALS AND FORMALDEHYDE FNG RESEARCH CO., LTD. (KR) 2018-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11090247-B2 Compositions for protecting the skin from heavy metals and formaldehyde FSCN1, SLC40A1, HCN2 HDAC4 93/4885HDAC6 376/4885ALDH1A1 675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.