Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 3/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23009636 | 0.89 | RIPK1 (0.49) | F11RIPK1PRMT5WDR77HSD11B1 | |
| SCHEMBL23009601 | 0.84 | F11 (0.53) | F11RIPK1PRMT5WDR77HSD11B1 | |
| SCHEMBL4019469 | 0.78 | RIPK1 (0.62) | RIPK1PRMT5WDR77HSD11B1AGTR2 | |
| SCHEMBL24234038 | 0.73 | RIPK1 (0.60) | RIPK1PRMT5WDR77HSD11B1EPHX2 | |
| SCHEMBL9336982 | 0.72 | RIPK1 (0.63) | RIPK1PRMT5WDR77HSD11B1EPHX2 | |
| SCHEMBL19917196 | 0.72 | HSD11B1 (0.59) | RIPK1PRMT5WDR77HSD11B1EPHX2 | |
| SCHEMBL24365000 | 0.72 | RIPK1 (0.63) | RIPK1PRMT5WDR77HSD11B1EPHX2 | |
| SCHEMBL216202 | 0.72 | RIPK1 (0.62) | RIPK1PRMT5WDR77HSD11B1EPHX2 | |
| SCHEMBL27574934 | 0.72 | RIPK1 (0.62) | RIPK1PRMT5WDR77HSD11B1EPHX2 | |
| SCHEMBL27574946 | 0.72 | RIPK1 (0.62) | RIPK1PRMT5WDR77HSD11B1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778588-A1 | QUATERNARY LACTAM COMPOUND AND PHARMACEUTICAL USE THEREOF | Shanghai Meiyue Biotech Development Co., Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |