Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 4/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20611183 | 0.85 | STING1 (0.36) | NT5ESLC29A1 | |
| SCHEMBL23010194 | 0.84 | NT5E (0.33) | NT5ESLC29A1P2RY1P2RY2 | |
| SCHEMBL22474927 | 0.84 | ADORA3 (0.39) | SLC29A1 | |
| SCHEMBL19187036 | 0.81 | NT5E (0.41) | NT5ESLC29A1P2RY1P2RY2FUT5 | |
| SCHEMBL23348445 | 0.78 | CYP3A4 (0.36) | — | |
| SCHEMBL20754387 | 0.77 | SLC29A1 (0.33) | SLC29A1 | |
| SCHEMBL15678090 | 0.76 | P2RY1 (0.43) | P2RY1P2RY2ENPP1 | |
| SCHEMBL19778461 | 0.75 | ADORA3 (0.41) | NT5EP2RY1 | |
| SCHEMBL19186747 | 0.74 | NT5E (0.41) | NT5EP2RY1P2RY2FUT5ENPP1 | |
| SCHEMBL19778378 | 0.74 | FUT5 (0.53) | NT5EP2RY2FUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935303-B1 | 4'-FLUORO-NUCLEOSIDES, 4'-FLUORO-NUCLEOTIDES AND ANALOGS THEREOF FOR THE TREATMENT OF HCV | JANSSEN BIOPHARMA INC (US) | 2021-02-17 | — | — | EP | disclosed |