Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 18/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.33 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23009999 | 0.85 | PARP1 (0.40) | PARP1PARP2TNKSPARP14PARP10 | |
| SCHEMBL24773304 | 0.79 | PARP1 (0.36) | PARP1PARP2TNKSPARP14PARP10 | |
| SCHEMBL21054554 | 0.78 | CFTR (0.38) | — | |
| SCHEMBL21054553 | 0.78 | CFTR (0.38) | — | |
| SCHEMBL30746029 | 0.78 | CFTR (0.38) | — | |
| SCHEMBL29192765 | 0.77 | NNMT (0.34) | PARP1PARP2 | |
| SCHEMBL22524695 | 0.75 | FFAR2 (0.34) | PARP1FFAR2 | |
| SCHEMBL30106504 | 0.75 | KDM5A (0.37) | PARP1FFAR2 | |
| SCHEMBL22975146 | 0.72 | CFTR (0.31) | PARP1 | |
| SCHEMBL31672108 | 0.72 | CFTR (0.31) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030554-A1 | PROCESS OF MAKING CFTR MODULATORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-02-18 | — | — | WO | disclosed |