Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23009999 | 0.89 | PARP1 (0.40) | CNR2SCN10AACACBFFAR2PARP1 | |
| SCHEMBL24070524 | 0.77 | ALDH1A1 (0.35) | KDM5AKDM4CCNR2SCN10AACACB | |
| SCHEMBL17648603 | 0.77 | CFTR (0.39) | POLBTDP1L3MBTL1KMT2A | |
| SCHEMBL29146243 | 0.76 | KMT2A (0.38) | CNR2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21323394 | 0.75 | KIF18A (0.40) | SCN10AFFAR2KIF18A | |
| SCHEMBL23010272 | 0.75 | PARP1 (0.39) | FFAR2PARP1 | |
| SCHEMBL25300913 | 0.74 | CNR2 (0.45) | CNR2SCN10APOLBTDP1L3MBTL1 | |
| SCHEMBL30562372 | 0.74 | SCN10A (0.56) | SCN10A | |
| SCHEMBL25389585 | 0.74 | SCN10A (0.56) | SCN10A | |
| SCHEMBL22120568 | 0.73 | KIF18A (0.41) | SCN10AKIF18APOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551867-A | Fused tricyclic compound, pharmaceutical composition and application thereof | 劲方医药科技(上海)有限公司 | 2022-12-30 | — | — | CN | disclosed |