Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 4/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27752824 | 0.81 | AR (0.43) | KIF11IDO1CA12CA1CA2 | |
| SCHEMBL2964967 | 0.79 | HSP90AA1 (0.41) | KIF11IDO1HSP90AA1HSP90AB1POLQ | |
| SCHEMBL19491471 | 0.78 | KIF11 (0.40) | KIF11IDO1HSP90AA1HSP90AB1POLQ | |
| SCHEMBL2596506 | 0.77 | ALDH1A1 (0.36) | CA2ALDH1A1 | |
| SCHEMBL30892375 | 0.77 | ALDH1A1 (0.36) | CA2ALDH1A1 | |
| SCHEMBL2297172 | 0.77 | KIF11 (0.39) | KIF11IDO1HSP90AA1HSP90AB1POLQ | |
| SCHEMBL19461657 | 0.77 | SLC6A4 (0.40) | KIF11IDO1POLQPOLBGAA | |
| SCHEMBL3873033 | 0.75 | KIF11 (0.47) | KIF11IDO1HSP90AA1HSP90AB1KDM1A | |
| Hydrochloric Acid SCHEMBL19461834 | 0.75 | SLC6A4 (0.40) | KIF11IDO1POLQPOLBGAA | |
| SCHEMBL1588990 | 0.74 | KIF11 (0.45) | KIF11CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103063-A1 | THERAPEUTIC COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-08-25 | — | — | WO | disclosed |