Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479644 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4EPOLBGAAAPOBEC3A | |
| SCHEMBL28707166 | 0.88 | HPSE (0.39) | ALDH1A1KDM4EPOLBGAAAPOBEC3A | |
| SCHEMBL29479687 | 0.88 | HPSE (0.39) | ALDH1A1KDM4EPOLBGAAAPOBEC3A | |
| SCHEMBL28711037 | 0.84 | KDM4E (0.38) | ALDH1A1KDM4EPOLBGAANPC1 | |
| SCHEMBL23033644 | 0.83 | HDAC6 (0.40) | ALDH1A1KDM4EPOLBHPSENPC1 | |
| SCHEMBL23033561 | 0.81 | PIM1 (0.55) | HPSE | |
| SCHEMBL23033423 | 0.80 | HDAC6 (0.38) | ALDH1A1KDM4EPOLBHPSENPC1 | |
| SCHEMBL28714646 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1KDM4EPOLBGAAHPSE | |
| SCHEMBL29479612 | 0.80 | SMN1; SMN2 (0.42) | ALDH1A1KDM4EPOLBGAAHPSE | |
| SCHEMBL23033684 | 0.80 | HPSE (0.42) | ALDH1A1KDM4EPOLBGAAHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |