Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.39 |
| ▸ | GSK3B | P49841 | 7/20 | 0.39 |
| ▸ | WNT1 | P04628 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479612 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL23033644 | 0.84 | HDAC6 (0.40) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL28713881 | 0.83 | ALDH1A1 (0.39) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL23033305 | 0.83 | HDAC6 (0.40) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL23033423 | 0.83 | HDAC6 (0.38) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL23033684 | 0.81 | HPSE (0.42) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL29479679 | 0.81 | HPSE (0.42) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL23012526 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL29479644 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2NPC1HPGDRAB9AALDH1A1 | |
| SCHEMBL23033561 | 0.80 | PIM1 (0.55) | HPSEDYRK1AGSK3BWNT1CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |