SCHEMBL23012804

SCHEMBL23012804

C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1C(c1ccccc1)c1nnn(C)n1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMARCA2 P51531 1/20 0.42
SMARCA4 P51532 1/20 0.42
PBRM1 Q86U86 1/20 0.42
ABCB1 P08183 1/20 0.39
USP30 Q70CQ3 6/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ATM Q13315 1/20 0.38
SETD7 Q8WTS6 1/20 0.38
DPP8 Q6V1X1 3/20 0.38
GPR119 Q8TDV5 1/20 0.38
GLS O94925 1/20 0.37
HPGDS O60760 1/20 0.37
TP53 P04637 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28707277 1.00 SMARCA2 (0.42) SMARCA2SMARCA4PBRM1ABCB1USP30
SCHEMBL23012137 0.85 GHSR (0.42) SMARCA2SMARCA4PBRM1ABCB1USP30
SCHEMBL23033355 0.84 KMT2A (0.48) MEN1KMT2AATMGPR119GLS
SCHEMBL23012077 0.83 SMARCA2 (0.42) SMARCA2SMARCA4PBRM1ABCB1USP30
SCHEMBL23034197 0.81 USP30 (0.40) USP30MEN1KMT2AATMGPR119
SCHEMBL29479763 0.80 MEN1 (0.39) USP30MEN1KMT2AATMGPR119
SCHEMBL29479717 0.80 EGFR (0.38) USP30MEN1KMT2AATMGPR119
SCHEMBL31165945 0.80 ATM (0.41) USP30MEN1KMT2AATMGPR119
SCHEMBL10073179 0.78 CCR5 (0.48) SMARCA2SMARCA4PBRM1ABCB1USP30
SCHEMBL29479761 0.78 CYP2D6 (0.48) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114269725-B Anti-influenza virus compound, preparation method and application thereof 西藏海思科制药有限公司 2024-09-17 CN disclosed
US-20230079045-A1 ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) 2023-03-16 US disclosed
CN-114269725-A Anti-influenza virus compound and preparation method and application thereof 四川海思科制药有限公司 2022-04-01 CN disclosed
WO-2021032209-A1 ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF 四川海思科制药有限公司 2021-02-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230079045-A1 ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF IDE, ACE, SI SMARCA2 1270/4885SMARCA4 1135/4885PBRM1 2397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.