Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29692226 | 1.00 | PDE2A (0.38) | PDE2AALDH1A1HPGDKDM4ETGFBR1 | |
| SCHEMBL29692238 | 0.89 | PDE2A (0.39) | PDE2AALDH1A1HPGDKDM4ETGFBR1 | |
| SCHEMBL23013420 | 0.89 | PDE2A (0.39) | PDE2AALDH1A1HPGDKDM4ETGFBR1 | |
| SCHEMBL29939163 | 0.87 | NOS2 (0.41) | PDE2AALDH1A1HPGDKDM4ETGFBR1 | |
| SCHEMBL29939592 | 0.87 | ALDH1A1 (0.40) | PDE2AALDH1A1HPGDKDM4ETGFBR1 | |
| SCHEMBL29939566 | 0.87 | ALDH1A1 (0.40) | PDE2AALDH1A1HPGDKDM4ETGFBR1 | |
| SCHEMBL23023716 | 0.82 | KDM4E (0.44) | PDE2AALDH1A1HPGDKDM4ETGFBR1 | |
| SCHEMBL29939563 | 0.80 | JAK2 (0.47) | PDE2AALDH1A1HPGDKDM4ETGFBR1 | |
| SCHEMBL29939370 | 0.79 | SLC34A1 (0.45) | PDE2AALDH1A1HPGDKDM4ETGFBR1 | |
| SCHEMBL29939355 | 0.79 | PDE2A (0.42) | PDE2AALDH1A1HPGDKDM4ETGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12227507-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2025-02-18 | — | — | US | disclosed |
| CN-114555604-B | Pharmaceutical compounds | 辉瑞公司 | 2024-11-15 | — | — | CN | disclosed |
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
| US-20220324873-A1 | PHARMACEUTICAL COMPOUNDS | PFIZER INC. | 2022-10-13 | — | — | US | disclosed |
| US-20220306639-A1 | PHARMACEUTICAL COMPOUNDS | PFIZER INC. | 2022-09-29 | — | — | US | disclosed |
| EP-4017856-A1 | PHARMACEUTICAL COMPOUNDS | Reviral Limited (GB) | 2022-06-29 | — | — | EP | disclosed |
| CN-114555604-A | Pharmaceutical compounds | 瑞威有限公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021032992-A1 | PHARMACEUTICAL COMPOUNDS | ReViral Limited (GB) | 2021-02-25 | — | — | WO | disclosed |
| WO-2021032992-A1 | PHARMACEUTICAL COMPOUNDS | ReViral Limited (GB) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12227507-B2 | Pharmaceutical compounds | CHRNA6, GABRA6, CHRNA7 | PDE2A 4652/4885ALDH1A1 3480/4885HPGD 3391/4885 |
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | PDE2A 4484/4885ALDH1A1 3010/4885HPGD 3197/4885 |
| US-20220306639-A1 | PHARMACEUTICAL COMPOUNDS | CHRNA6, GABRA6, CHRNA7 | PDE2A 4652/4885ALDH1A1 3480/4885HPGD 3391/4885 |
| US-20220324873-A1 | PHARMACEUTICAL COMPOUNDS | GABRA6, CNR1, CHRNA6 | PDE2A 4480/4885ALDH1A1 3112/4885HPGD 3337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.