Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29939566 | 0.86 | ALDH1A1 (0.40) | KDM4ENPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL29939592 | 0.86 | ALDH1A1 (0.40) | KDM4EKMT2AJAK2JAK3ALDH1A1 | |
| SCHEMBL29692297 | 0.83 | JAK2 (0.40) | KDM4ENPC1RAB9ARXFP1JAK2 | |
| SCHEMBL23013103 | 0.83 | JAK2 (0.40) | KDM4ENPC1RAB9ARXFP1JAK2 | |
| SCHEMBL23013420 | 0.83 | PDE2A (0.39) | KDM4EJAK2JAK3ALDH1A1HPGD | |
| SCHEMBL29692238 | 0.83 | PDE2A (0.39) | KDM4EJAK2JAK3ALDH1A1HPGD | |
| SCHEMBL23013307 | 0.82 | PDE2A (0.38) | KDM4EALDH1A1HPGDADORA3TGFBR1 | |
| SCHEMBL29692226 | 0.82 | PDE2A (0.38) | KDM4EALDH1A1HPGDADORA3TGFBR1 | |
| SCHEMBL29939163 | 0.81 | NOS2 (0.41) | KDM4EJAK2JAK3ALDH1A1HPGD | |
| SCHEMBL25150706 | 0.79 | DGAT1 (0.45) | KDM4ENPC1RAB9ARXFP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
| WO-2021032992-A1 | PHARMACEUTICAL COMPOUNDS | ReViral Limited (GB) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | KDM4E 3774/4885NPC1 605/4885RAB9A 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.