Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014221 | 0.95 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23014633 | 0.89 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23014191 | 0.88 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23014627 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23014224 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23014520 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23014634 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23014067 | 0.87 | KEAP1 (0.46) | ALDH1A1TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23014638 | 0.87 | L3MBTL1 (0.50) | ALDH1A1TSHRCYP3A4CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL23014063 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220305121-A1 | N-ARYL SULFONAMIDE DERIVATIVES AS VACCINE ADJUVANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-09-29 | — | — | US | disclosed |
| WO-2021034729-A1 | N-ARYL SULFONAMIDE DERIVATIVES AS VACCINE ADJUVANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220305121-A1 | N-ARYL SULFONAMIDE DERIVATIVES AS VACCINE ADJUVANT | TLR1, TLR3, TLR2 | ALDH1A1 4133/4885TSHR 2287/4885CYP3A4 4355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.