Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014674 | 0.84 | HTT (0.53) | L3MBTL1BRD4ACLYSLC40A1ALDH1A1 | |
| SCHEMBL23014677 | 0.82 | KDM4E (0.46) | BRD4KDM4EHPGD | |
| SCHEMBL14875820 | 0.81 | ACLY (0.52) | L3MBTL1BRD4ACLYSLC40A1ALDH1A1 | |
| SCHEMBL163954 | 0.79 | KMT2A (0.43) | L3MBTL1BRD4ACLYSLC40A1ALDH1A1 | |
| SCHEMBL1894761 | 0.75 | L3MBTL1 (0.58) | L3MBTL1BRD4ACLYSLC40A1ALDH1A1 | |
| SCHEMBL28751799 | 0.72 | BRD4 (0.56) | L3MBTL1BRD4ALDH1A1KDM4EKMT2A | |
| SCHEMBL30547366 | 0.72 | L3MBTL1 (0.55) | L3MBTL1BRD4ACLYSLC40A1ALDH1A1 | |
| SCHEMBL5700122 | 0.72 | L3MBTL1 (0.55) | L3MBTL1BRD4ACLYSLC40A1ALDH1A1 | |
| SCHEMBL5255932 | 0.72 | L3MBTL1 (0.43) | L3MBTL1BRD4ACLYSLC40A1ALDH1A1 | |
| SCHEMBL12411094 | 0.71 | L3MBTL1 (0.54) | L3MBTL1BRD4ACLYSLC40A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12540115-B2 | Inhibitors of phospholipid synthesis and methods of use | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2026-02-03 | — | — | US | disclosed |
| US-20220315528-A1 | INHIBITORS OF PHOSPHOLIPID SYNTHESIS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-10-06 | — | — | US | disclosed |
| WO-2021035031-A1 | INHIBITORS OF PHOSPHOLIPID SYNTHESIS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315528-A1 | INHIBITORS OF PHOSPHOLIPID SYNTHESIS AND METHODS OF USE | LCAT, AGPAT2, AGPAT5 | L3MBTL1 2500/4885BRD4 761/4885ACLY 879/4885 |
| US-12540115-B2 | Inhibitors of phospholipid synthesis and methods of use | LCAT, DGAT1, DGAT2 | L3MBTL1 2093/4885BRD4 1607/4885ACLY 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.