Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.68 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21117079 | 1.00 | PSIP1 (0.68) | PSIP1ALOX5APFEN1 | |
| SCHEMBL22778265 | 0.94 | PSIP1 (0.72) | PSIP1ALOX5APFEN1 | |
| SCHEMBL12459797 | 0.87 | PSIP1 (0.77) | PSIP1ALOX5APFEN1 | |
| SCHEMBL10886862 | 0.83 | PGAM1 (0.51) | — | |
| SCHEMBL17269669 | 0.83 | KDM4E (0.50) | — | |
| SCHEMBL3712510 | 0.81 | PSIP1 (1.00) | PSIP1ALOX5APFEN1 | |
| SCHEMBL9902296 | 0.81 | KDM4E (0.49) | — | |
| SCHEMBL10586511 | 0.81 | KDM4E (0.49) | — | |
| SCHEMBL11442426 | 0.81 | PGAM1 (0.52) | — | |
| SCHEMBL9902654 | 0.80 | ALOX5AP (0.58) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12540115-B2 | Inhibitors of phospholipid synthesis and methods of use | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2026-02-03 | — | — | US | disclosed |
| US-20220315528-A1 | INHIBITORS OF PHOSPHOLIPID SYNTHESIS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-10-06 | — | — | US | disclosed |
| WO-2021035031-A1 | INHIBITORS OF PHOSPHOLIPID SYNTHESIS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315528-A1 | INHIBITORS OF PHOSPHOLIPID SYNTHESIS AND METHODS OF USE | LCAT, AGPAT2, AGPAT5 | PSIP1 679/4885ALOX5AP 276/4885FEN1 3114/4885 |
| US-12540115-B2 | Inhibitors of phospholipid synthesis and methods of use | LCAT, DGAT1, DGAT2 | PSIP1 692/4885ALOX5AP 391/4885FEN1 4525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.