SCHEMBL25570523

SCHEMBL25570523

CN[C@H](CCCCN)C(=O)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.40
GSR P00390 1/20 0.38
CPB2 Q96IY4 7/20 0.38
SIRT6 Q8N6T7 1/20 0.38
SIRT1 Q96EB6 1/20 0.38
RNPEP Q9H4A4 1/20 0.37
GNAI3 P08754 1/20 0.35
GNAO1 P09471 1/20 0.35
GNAI1 P63096 1/20 0.35
SLC6A5 Q9Y345 1/20 0.35
MMP1 P03956 1/20 0.34
MMP3 P08254 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22375523 1.00 FOLH1 (0.40) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL20402783 0.98 CPB2 (0.41) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL24658920 0.87 FOLH1 (0.39) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL22859968 0.85 FOLH1 (0.40) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL10047161 0.85 FOLH1 (0.40) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL13891963 0.85 FOLH1 (0.40) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL19483433 0.84 CPB2 (0.41) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL19483432 0.84 CPB2 (0.41) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL21566733 0.82 SIRT6 (0.52) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL24379977 0.82 FOLH1 (0.41) FOLH1GSRCPB2SIRT6SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174985-A1 MODIFIED PEPTIDE NUCLEIC ACID COMPOSITIONS NEUBASE THERAPEUTICS, INC. 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174985-A1 MODIFIED PEPTIDE NUCLEIC ACID COMPOSITIONS TARDBP, SARNP, SNRPE FOLH1 1495/4885GSR 2434/4885CPB2 1892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.