Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 7/20 | 0.54 |
| ▸ | ANXA2 | P07355 | 2/20 | 0.50 |
| ▸ | S100A10 | P60903 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233272 | 0.93 | CCR1 (0.52) | CCR1ANXA2S100A10RXFP1KDM4E | |
| SCHEMBL2233975 | 0.88 | ANXA2 (0.49) | CCR1ANXA2S100A10RXFP1KDM4E | |
| SCHEMBL10146036 | 0.80 | RXFP1 (0.69) | CCR1RXFP1KDM4EHPGDP2RX3 | |
| SCHEMBL2235286 | 0.80 | ANXA2 (0.67) | CCR1ANXA2S100A10MEN1KMT2A | |
| SCHEMBL10116868 | 0.79 | KDM4E (0.65) | CCR1RXFP1KDM4EHPGDP2RX3 | |
| SCHEMBL2232399 | 0.78 | CCR1 (0.54) | CCR1ANXA2S100A10RXFP1KDM4E | |
| SCHEMBL2232358 | 0.78 | CCR1 (0.59) | CCR1ANXA2S100A10RXFP1KDM4E | |
| SCHEMBL10116779 | 0.77 | P2RX3 (0.56) | CCR1RXFP1KDM4EHPGDP2RX3 | |
| SCHEMBL10120635 | 0.76 | CCR1 (0.69) | CCR1RXFP1KDM4EHPGDP2RX3 | |
| SCHEMBL10120633 | 0.76 | CCR1 (0.65) | CCR1RXFP1KDM4EHPGDP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092505-A1 | S100 PROTEIN BINDING INTERACTION INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |