Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 14/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21324685 | 1.00 | EPHX1 (0.53) | EPHX1EPHX2ALDH1A1KDM4EUSP30 | |
| SCHEMBL23585198 | 0.96 | EPHX1 (0.53) | EPHX1EPHX2ALDH1A1KDM4EUSP30 | |
| SCHEMBL18124056 | 0.82 | ALDH1A1 (0.47) | EPHX1EPHX2ALDH1A1USP30 | |
| SCHEMBL23019793 | 0.81 | USP30 (0.52) | EPHX1EPHX2ALDH1A1KDM4EUSP30 | |
| SCHEMBL13772760 | 0.74 | HPGD (0.45) | EPHX1ALDH1A1 | |
| SCHEMBL24033437 | 0.74 | EPHX1 (0.49) | EPHX1ALDH1A1USP30 | |
| SCHEMBL20004096 | 0.73 | CTSK (0.48) | EPHX1EPHX2ALDH1A1KDM4EUSP30 | |
| SCHEMBL23638806 | 0.73 | CTSK (0.48) | EPHX1EPHX2ALDH1A1KDM4EUSP30 | |
| SCHEMBL16763600 | 0.73 | EPHX1 (0.53) | EPHX1EPHX2ALDH1A1KDM4EUSP30 | |
| SCHEMBL16763601 | 0.73 | EPHX1 (0.53) | EPHX1EPHX2ALDH1A1KDM4EUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3277677-B9 | 1-CYANO-PYRROLIDINE COMPOUNDS AS USP30 INHIBITORS | MISSION THERAPEUTICS LTD (GB) | 2021-07-14 | — | — | EP | disclosed |
| EP-3277677-B1 | 1-CYANO-PYRROLIDINE COMPOUNDS AS USP30 INHIBITORS | MISSION THERAPEUTICS LTD (GB) | 2021-02-24 | — | — | EP | disclosed |