Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | CCR4 | P51679 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607425 | 0.79 | CRHR1 (0.42) | HRH3CCR4 | |
| SCHEMBL28937980 | 0.79 | CRHR1 (0.42) | HRH3CCR4 | |
| SCHEMBL20612065 | 0.78 | HCAR3 (0.43) | CCR4 | |
| SCHEMBL28277650 | 0.78 | HCAR3 (0.43) | CCR4 | |
| SCHEMBL19402117 | 0.77 | MAPK9 (0.34) | MAPK9MAPK10GRM5 | |
| SCHEMBL21378510 | 0.74 | FYN (0.44) | — | |
| SCHEMBL19692970 | 0.74 | FYN (0.44) | — | |
| SCHEMBL1774897 | 0.73 | GAA (0.42) | MAPK10GRM5 | |
| SCHEMBL21550282 | 0.72 | ESR1 (0.35) | SYKCCR4GRM5 | |
| SCHEMBL20685774 | 0.72 | MAPK14 (0.42) | MAPK9GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3434674-B1 | ((4-(2-OXOIMIDAZOLIDINE-1-YL)PYRIMIDIN-2-YL)AMINE DERIVATIVES AS MUTANT IDH INHIBITORS FOR TREATING CANCER | SHANGHAI HAIHE PHARMACEUTICAL CO LTD (CN) | 2021-02-24 | — | — | EP | disclosed |