Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 12/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607425 | 1.00 | CRHR1 (0.42) | CRHR1HCAR3HCAR2HRH3CCNA2 | |
| SCHEMBL21378510 | 0.90 | FYN (0.44) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL19692970 | 0.90 | FYN (0.44) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL20612065 | 0.84 | HCAR3 (0.43) | HCAR3ESR1CCR4 | |
| SCHEMBL28277650 | 0.84 | HCAR3 (0.43) | HCAR3ESR1CCR4 | |
| SCHEMBL1774897 | 0.79 | GAA (0.42) | HCAR3ESR1 | |
| SCHEMBL23019896 | 0.79 | MAPK9 (0.33) | HRH3CCR4 | |
| SCHEMBL12393896 | 0.79 | HRH3 (0.56) | HRH3CCNA2CDK2CDK5DYRK1A | |
| SCHEMBL21550282 | 0.78 | ESR1 (0.35) | CCNA2CDK2ESR1CCR4 | |
| SCHEMBL20685774 | 0.78 | MAPK14 (0.42) | HCAR3CDK5DYRK1BCDK9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341145-A | Chemical compound | 博拉公司 | 2022-04-12 | — | — | CN | disclosed |