Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14708930 | 0.80 | UTS2R (0.36) | BCAT2UTS2RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17970597 | 0.74 | KDM4E (0.46) | CYP2C19LMNAALDH1A1POLBKDM4E | |
| SCHEMBL3693598 | 0.73 | MEN1 (0.47) | UTS2RSLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL9763706 | 0.71 | RAD52 (0.47) | SLC6A4LMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8208884 | 0.69 | L3MBTL1 (0.49) | BCAT2CYP3A4TSHRLMNAALDH1A1 | |
| SCHEMBL8579457 | 0.69 | LMNA (0.46) | BCAT2CYP3A4CYP2C19TSHRLMNA | |
| SCHEMBL14708928 | 0.69 | POLB (0.38) | BCAT2UTS2RSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6555816 | 0.68 | BCAT2 (0.62) | BCAT2CYP1A2LMNAALDH1A1POLB | |
| SCHEMBL47640 | 0.68 | OPRM1 (0.39) | UTS2RCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10209861 | 0.67 | LMNA (0.47) | BCAT2TSHRLMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782649-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | Ascendis Pharma A/S (DK) | 2021-02-24 | — | — | EP | disclosed |