Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.32 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2698890 | 0.80 | ALOX15 (0.41) | LMNAHSD17B10CHRM5CHRM1CHRM3 | |
| SCHEMBL396764 | 0.79 | TSHR (0.47) | ALDH1A1TDP1TSHR | |
| SCHEMBL8839347 | 0.75 | ALDH1A1 (0.47) | ALDH1A1LMNAHSD17B10CHRM5CHRM1 | |
| SCHEMBL15112881 | 0.69 | — | — | |
| SCHEMBL16610457 | 0.69 | — | — | |
| SCHEMBL15312452 | 0.65 | ALDH1A1 (0.34) | ALDH1A1TSHRGAAMGAMSI | |
| SCHEMBL14576463 | 0.64 | TSHR (0.39) | ALDH1A1LMNAHSD17B10TDP1CHRM5 | |
| SCHEMBL25628009 | 0.64 | TDP1 (0.45) | ALDH1A1LMNAHSD17B10TDP1CHRM5 | |
| SCHEMBL784658 | 0.64 | TDP1 (0.45) | ALDH1A1LMNAHSD17B10TDP1CHRM5 | |
| SCHEMBL331418 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102812031-B | Silaoxacyclen | WACKER CHEMIE AG (DE) | 2015-10-07 | — | — | CN | disclosed |
| EP-2550281-B1 | SILAOXACYCLES | WACKER CHEMIE AG (DE) | 2014-06-25 | — | — | EP | disclosed |
| US-8722914-B2 | Silaoxacycles | WACKER CHEMIE AG (DE) | 2014-05-13 | — | — | US | disclosed |
| EP-2539350-B1 | METHOD FOR PRODUCING ESTER-FUNCTIONAL SILANES | WACKER CHEMIE AG (DE) | 2013-09-18 | — | — | EP | disclosed |
| US-20130060057-A1 | METHOD FOR PRODUCING ESTER-FUNCTIONAL SILANES | WACKER CHEMIE AG (DE) | 2013-03-07 | — | — | US | disclosed |
| EP-2550281-A1 | SILAOXACYCLEN | Wacker Chemie AG (DE) | 2013-01-30 | — | — | EP | disclosed |
| US-20130018200-A1 | SILAOXACYCLES | WACKER CHEMIE AG (DE) | 2013-01-17 | — | — | US | disclosed |
| EP-2539350-A1 | METHOD FOR PRODUCING ESTER-FUNCTIONAL SILANES | Wacker Chemie AG (DE) | 2013-01-02 | — | — | EP | disclosed |
| CN-102812031-A | Silaoxacyclen | WACKER CHEMIE AG | 2012-12-05 | — | — | CN | disclosed |
| CN-102762579-A | Method for producing ester-functional silanes | WACKER CHEMIE AG | 2012-10-31 | — | — | CN | disclosed |
| WO-2011117071-A1 | SILAOXACYCLEN | WACKER CHEMIE AG (DE) | 2011-09-29 | — | — | WO | disclosed |
| WO-2011101278-A1 | METHOD FOR PRODUCING ESTER-FUNCTIONAL SILANES | WACKER CHEMIE AG (DE) | 2011-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018200-A1 | SILAOXACYCLES | CCNO, PCNA, CCNA2 | ALDH1A1 744/4885LMNA 423/4885HSD17B10 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.