SCHEMBL396764

SCHEMBL396764

C=C(C)C(=O)OC[SiH2]C(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
ALDH1A1 P00352 2/20 0.41
THRB P10828 1/20 0.40
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3206550 0.86 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL4445992 0.85 THRB (0.37) TSHRALDH1A1THRB
SCHEMBL65597 0.81 THRB (0.46) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL3915024 0.81 TSHR (0.48) TSHRALDH1A1THRB
SCHEMBL580729 0.81 THRB (0.50) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL3914287 0.81 TSHR (0.41) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL393526 0.80 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL136875 0.79 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL537010 0.79 TSHR (0.46) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL16537856 0.78 TSHR (0.53) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110198030-A1 POLYURETHANE COMPOSITION THAT CONTAINS ALPHA-SILANE AND THAT HAS ANISOTROPIC MATERIAL PROPERTIES SIKA TECHNOLOGY AG (CH) 2011-08-18 US claimed
EP-2189485-B1 Polyurethane composition comprising alpha-silane having anisostropic material properties SIKA TECHNOLOGY AG (CH) 2011-02-16 EP claimed
EP-2189485-A1 Polyurethane composition comprising alpha-silane having anisostropic material properties Sika Technology AG (CH) 2010-05-26 EP claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 EP claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
EP-3585851-B1 AIR AND WATER BARRIER ARTICLE INCLUDING INELASTIC POROUS LAYER 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-01 EP disclosed
US-12403671-B2 Roll including air and water barrier article and method of using the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-09-02 US disclosed
EP-3941952-B1 THERMOPLASTIC ELASTOMER COMPOSITION HAVING LOW DENSITY AND GOOD MECHANICAL PROPERTIES BY USING UNCOATED HOLLOW GLASS SPHERES KRAIBURG TPE GMBH & CO KG (DE) 2025-04-30 EP disclosed
EP-3108076-B1 EASY TO APPLY AIR AND WATER BARRIER ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-03-26 EP disclosed
US-12227936-B2 Tape, article including tape and composite layer, and related methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-02-18 US disclosed
CN-113631598-B Thermoplastic elastomer composition with low density and good mechanical properties by using uncoated hollow glass microspheres 克赖布尔格TPE有限责任两合公司 2024-12-20 CN disclosed
EP-3337867-B1 AIR AND WATER BARRIER ARTICLE WITH POROUS LAYER AND LINER 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-04-10 EP disclosed
WO-2006117338-A2 MOISTURE-CURABLE COMPOSITION FEATURING INCREASED ELASTICITY SIKA TECHNOLOGY AG (CH) 2006-11-09 WO disclosed
EP-1717254-A1 Moisture-curable composition with improved elongation Sika Technology AG (CH) 2006-11-02 EP disclosed
WO-2006072411-A1 CROSS-LINKABLE, SILANE-MODIFIED COPOLYMERS WACKER CHEMIE AG (DE) 2006-07-13 WO disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 EP disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 TSHR 4650/4885ALDH1A1 402/4885THRB 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.