SCHEMBL2302235

SCHEMBL2302235

O=[N+]([O-])c1ccc(N=Nc2ccc(Nc3ccccc3)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.79
ALOX12 P18054 1/20 0.79
L3MBTL1 Q9Y468 1/20 0.79
MEN1 O00255 10/20 0.69
KMT2A Q03164 10/20 0.69
MAPT P10636 6/20 0.69
RAB9A P51151 6/20 0.69
MAPK1 P28482 4/20 0.69
ALDH1A1 P00352 4/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
CASP3 P42574 1/20 0.69
SENP8 Q96LD8 1/20 0.69
SENP7 Q9BQF6 1/20 0.69
SENP6 Q9GZR1 1/20 0.69
CXCR2 P25025 1/20 0.63
NPC1 O15118 5/20 0.53
HTT P42858 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
KDM4E B2RXH2 2/20 0.53
GLA P06280 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL769328 1.00 HPGD (0.79) HPGDALOX12L3MBTL1MEN1KMT2A
SCHEMBL28588133 0.97 HPGD (0.73) HPGDALOX12L3MBTL1MEN1KMT2A
SCHEMBL224794 0.89 ALOX12 (1.00) HPGDALOX12L3MBTL1MEN1KMT2A
SCHEMBL9479463 0.89 ALOX12 (1.00) HPGDALOX12L3MBTL1MEN1KMT2A
Hydrochloric Acid SCHEMBL3693418 0.87 ALOX12 (0.96) HPGDALOX12L3MBTL1MEN1KMT2A
SCHEMBL9717470 0.87 ALOX12 (0.96) HPGDALOX12L3MBTL1MEN1KMT2A
SCHEMBL270426 0.85 MEN1 (0.66) HPGDALOX12L3MBTL1MEN1KMT2A
SCHEMBL270425 0.85 MEN1 (0.66) HPGDALOX12L3MBTL1MEN1KMT2A
SCHEMBL29588234 0.85 MEN1 (0.66) HPGDALOX12L3MBTL1MEN1KMT2A
SCHEMBL28588136 0.85 KMT2A (0.58) HPGDALOX12L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119877298-A Preparation method of cool sense sorrel dyed fabric with antibacterial, moisture absorption and sweat release properties 河北宏润新型面料有限公司 2025-04-25 CN claimed
US-20250075051-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2025-03-06 US claimed
EP-4457275-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2024-11-06 EP claimed
CN-118745674-A Polyester low COD dyeing process 台州东海翔染整有限公司 2024-10-08 CN claimed
CN-116262831-B Preparation method and application of dispersing agent for liquid disperse dye 浙江科峰有机硅股份有限公司 2024-08-06 CN claimed
CN-118241497-A Dyeing method of blended fabric 武汉纺织大学 2024-06-25 CN claimed
CN-117626681-A D5 medium disperse dye dyeing process for negative oxygen ion PTT fabric 湖州福美达纺织有限公司 2024-03-01 CN claimed
CN-117247857-A Heat-resistant heavy metal-resistant mixed bacterial agent, bacterial strain and application thereof in azo dye decolorization 浙江工业大学 2023-12-19 CN claimed
CN-115216427-B Pseudomonas SX-10 and application thereof in azo dye decolorization 浙江工业大学 2023-07-14 CN claimed
WO-2023126441-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2023-07-06 WO claimed
JP-4750804-B2 2011-08-17 JP claimed
US-7611545-B2 Cosmetic article and process for dry dyeing keratin materials L'OREAL S.A. (FR) 2009-11-03 US claimed
US-20080306026-A1 Capsule Formulation SYNGENTA CROP PROTECTION LLC 2008-12-11 US claimed
US-20080244837-A1 Cosmetic article and process for dry dyeing keratin materials L'OREAL S.A. (FR) 2008-10-09 US claimed
EP-1964539-A1 Cosmetic article for dyeing dry hair, its use, method of implementing said article L'Oréal (FR) 2008-09-03 EP claimed
JP-2008531514-A 2008-08-14 JP claimed
US-20080148496-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation L'OREAL S.A. (FR) 2008-06-26 US claimed
EP-1850664-A2 PESTICIDAL CAPSULE FORMULATION Syngeta Participations AG (CH) 2007-11-07 EP claimed
WO-2006089747-A2 PRESTICIDAL CAPSULE FORMULATION SYNGENTA PARTICIPATIONS AG (CH) 2006-08-31 WO claimed
EP-0482593-B1 Polymer scale preventive agent, polymerization vessel for preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1995-01-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080244837-A1 Cosmetic article and process for dry dyeing keratin materials KRT18, CUTA, DSG1 HPGD 322/4885ALOX12 3058/4885L3MBTL1 4716/4885
US-20080148496-A1 Dyeing of in Particular Human Keratin Materials by Dry Thermal Transfer of a Direct Dye, Composition Comprising the Said Dye and Its Method of Preparation KRT18, IK, DSG1 HPGD 257/4885ALOX12 3516/4885L3MBTL1 4854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.