Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17602277 | 0.85 | ALDH1A1 (0.55) | SIGMAR1 | |
| SCHEMBL9520577 | 0.84 | KDM4C (0.53) | KDM4CHTR6SIGMAR1 | |
| SCHEMBL10467194 | 0.83 | HTR6 (0.58) | KDM4CHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9523635 | 0.83 | KDM4C (0.53) | KDM4CSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9520181 | 0.82 | HTR6 (0.57) | KDM4CHTR6SIGMAR1 | |
| SCHEMBL9521784 | 0.81 | KDM4C (0.52) | KDM4CHTR6SIGMAR1 | |
| SCHEMBL23023008 | 0.81 | HTR2A (0.55) | KDM4CHTR6 | |
| Hydrochloric Acid SCHEMBL9520744 | 0.81 | KDM4C (0.51) | KDM4CHTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL23004822 | 0.79 | HTR2A (0.54) | KDM4CHTR6 | |
| Hydrochloric Acid SCHEMBL30278324 | 0.79 | HTR2A (0.54) | KDM4CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053997-A1 | TRNA SYNTHETASE INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053997-A1 | TRNA SYNTHETASE INHIBITORS | TRMT1, AARS1, GARS1 | KDM4C 2071/4885HTR6 3542/4885HTR1A 3703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.