SCHEMBL7764111

SCHEMBL7764111

CCCCCCOC(=O)c1nn[nH]c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
MAPT P10636 3/20 0.48
ATM Q13315 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
GAA P10253 1/20 0.48
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.46
GPR84 Q9NQS5 1/20 0.46
ESR1 P03372 3/20 0.46
MMP2 P08253 1/20 0.45
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPK1 P28482 1/20 0.44
MMP1 P03956 1/20 0.43
MMP9 P14780 1/20 0.43
MMP12 P39900 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
AKR1C4 P17516 1/20 0.43
AKR1C3 P42330 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10553656 0.79 LMNA (0.46) LMNAMAPTATML3MBTL1GAA
SCHEMBL21572873 0.76 LMNA (0.57) LMNAMAPTATML3MBTL1GAA
SCHEMBL28329211 0.73 GPR84 (0.52) LMNAMAPTALDH1A1TSHRGPR84
SCHEMBL9588716 0.72 LMNA (0.50) LMNAL3MBTL1ALDH1A1TSHRGPR84
SCHEMBL11230500 0.71 LMNA (0.56) LMNAMAPTATML3MBTL1GAA
SCHEMBL11234134 0.71 LMNA (0.56) LMNAMAPTATML3MBTL1GAA
SCHEMBL11232238 0.71 LMNA (0.56) LMNAMAPTATML3MBTL1GAA
SCHEMBL11228075 0.71 LMNA (0.56) LMNAMAPTATML3MBTL1GAA
SCHEMBL9731053 0.71 NPSR1 (0.48) MAPTGAATSHRMAPK1RAB9A
SCHEMBL16358630 0.71 ALDH1A1 (0.51) LMNAMAPTALDH1A1TSHRGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0837363-B1 Photographic elements containing development inhibitor releasing compounds EASTMAN KODAK CO (US) 2001-05-09 EP disclosed
US-6043378-A CONTAINING AN IMAGE MODIFYING COMPOUND WHICH COMPRISES A MAGENTA COUPLER MOIETY WHICH UPON REACTION WITH OXIDIZED COLOR DEVELOPING AGENT DURING PROCESSING FORMS A DYE; STORAGE STABILITY EASTMAN KODAK COMPANY (US) 2000-03-28 US disclosed
US-5759757-A PYRAZOLO-1,2,3-TRIAZOLE DERIVATIVES AS IMAGE MODIFIERS; STORAGE STABILITY EASTMAN KODAK COMPANY (US) 1998-06-02 US disclosed
EP-0837363-A2 Photographic elements containing development inhibitor releasing compounds EASTMAN KODAK COMPANY (US) 1998-04-22 EP disclosed
US-5463072-A Process for the preparation of naphtholic 2-equivalent cyan couplers AGFA GEVART AG, D-51368 (DE) 1995-10-31 US disclosed
US-5021332-A Rapid develoopment inhibitor release AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed