SCHEMBL2302711

SCHEMBL2302711

C=CCCCCCNCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ABCC4 O15439 1/20 0.63
MAPT P10636 1/20 0.63
ALDH1A1 P00352 2/20 0.46
LMNA P02545 1/20 0.46
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
TSHR P16473 1/20 0.38
EPHX2 P34913 7/20 0.38
PRMT1 Q99873 1/20 0.38
LTA4H P09960 1/20 0.37
LPAR2 Q9HBW0 1/20 0.37
LPAR3 Q9UBY5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254002 1.00 ABCC4 (0.63) ABCC4MAPTALDH1A1LMNAMAOA
SCHEMBL29915565 0.96 ABCC4 (0.59) ABCC4MAPTALDH1A1LMNAMAOA
SCHEMBL16925547 0.94 ABCC4 (0.59) ABCC4MAPTALDH1A1LMNAMAOA
SCHEMBL93540 0.85
SCHEMBL18045567 0.84 MAOA (0.50) ALDH1A1LMNAMAOAMAOBTSHR
SCHEMBL18045569 0.84 MAOA (0.50) ALDH1A1LMNAMAOAMAOBTSHR
SCHEMBL30972193 0.84 ABCC4 (0.70) ABCC4MAPTALDH1A1LMNATSHR
SCHEMBL18045572 0.82 MAOA (0.46) ALDH1A1LMNAMAOAMAOBTSHR
SCHEMBL1033281 0.80 EPHX2 (0.42) MAPTLMNAEPHX2
SCHEMBL4808838 0.80 ABCC4 (0.44) ABCC4MAPTALDH1A1LMNAMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2351848-B1 METHOD FOR PRODUCING L-AMINO ACID KANEKA CORP (JP) 2018-02-28 EP disclosed
US-9464306-B2 Method for producing L-amino acid KANEKA CORPORATION (JP) 2016-10-11 US disclosed
CN-102203274-A Process for producing L-amino acid KANEKA CORP 2011-09-28 CN disclosed
US-20110229940-A1 METHOD FOR PRODUCING L-AMINO ACID KANEKA CORPORATION (JP) 2011-09-22 US disclosed
EP-2351848-A1 METHOD FOR PRODUCING L-AMINO ACID Kaneka Corporation (JP) 2011-08-03 EP disclosed
WO-2007148135-A1 MACROCYCLIC COMPOUNDS AS ANTIVIRAL AGENTS ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) 2007-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110229940-A1 METHOD FOR PRODUCING L-AMINO ACID ADSL, ASNS, AASDHPPT ABCC4 4680/4885MAPT 2698/4885ALDH1A1 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.