Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038420 | 1.00 | POLB (0.54) | POLBMMP8GAAPIN1TDP1 | |
| SCHEMBL4206097 | 0.90 | MMP8 (0.50) | POLBMMP8GAAPIN1TDP1 | |
| SCHEMBL9000765 | 0.88 | MMP8 (0.49) | POLBMMP8GAAPIN1TDP1 | |
| SCHEMBL6671021 | 0.88 | MMP8 (0.51) | POLBMMP8GAAPIN1TDP1 | |
| SCHEMBL28333199 | 0.87 | CYP1A2 (0.47) | POLBMMP8GAAKMT2AKDM4E | |
| SCHEMBL4886826 | 0.87 | MMP8 (0.48) | POLBMMP8GAAPIN1TDP1 | |
| SCHEMBL8818975 | 0.87 | MMP8 (0.48) | POLBMMP8GAAPIN1TDP1 | |
| SCHEMBL28066882 | 0.87 | MMP8 (0.48) | POLBMMP8GAAPIN1TDP1 | |
| SCHEMBL8564225 | 0.86 | GAA (0.52) | POLBMMP8GAAPIN1TDP1 | |
| SCHEMBL7684411 | 0.86 | SMN1; SMN2 (0.55) | POLBMMP8GAAPIN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | ADH5, HDHD5, ADH1A | POLB 622/4885MMP8 2095/4885GAA 1156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.